Levurin®
19,75 lei
Compozitie
Un plic cu pulbere orala Levurin® contine 250 mg pulbere liofilizata de Saccharomyces boulardii si 1000 mg de inulina.
Saccharomyces boulardii este o levura rezistenta la actiunea sucurilor gastrice si intestinale, a antibioticelor si a sulfamidelor, dar sensibila la actiunea antifungicelor sistemice si orale si a derivatilor de chinoleina (tulpina Saccharomyces boulardii Lessafre CNCM I – 3799 din produsul Levurin® este identica din punct de vedere genetic cu tulpina Hansen CBS 5926).
Inulina este un polizaharid al fructozei si apartine clasei de carbohidrati cunoscuta sub denumirea de fructani (inulina din produsul Levurin® este un extras standardizat, cu potential terapeutic controlat).
Mecanism de actiune
Saccharomyces boulardii poate interfera cu patogeneza in lumenul intestinal prin mai multe mecanisme: efectul anti-toxine patogene, efectul de a inhiba dezvoltarea unor agenti patogeni, efectul de a imbunatati integritatea jonctiunii intercelulare si efectul trofic asupra mucoasei intestinale.
Saccharomyces boulardii, atunci cand este administrat pe cale orala, atinge concentratii de echilibru in termen de 3 zile (in intestin subtire si colon) si este eliminat in decurs de 3-5 zile dupa ce este intrerupta administrarea.
Inulina din compozitia Levurin este un substrat de metabolizare de catre levura Saccharomyces boulardii si are astfel potentialul de a sustine mecanismul de actiune Saccharomyces boulardii.
Recomandare
Prin actiunea sinergica a celor doua componente, Levurin® are potential in:
– Preventia si tratamentul diareei asociate administrarii de antibiotic
– Preventia recurentelor infectiilor cu Clostridium difficilae
– Tratamentul diareei acute infectioase
Mod de administrare
La recomandarea medicului dumneavoastra, Levurin® se poate administra simultan cu doza de antibiotic.
Levurin® se recomanda adultilor si copiilor mai mari de 6 luni, prin administrarea pe cale orala a 1-2 plicuri/zi, dozele putand fi marite cu avizul medicului, daca nu exista contraindicatii.
Persoanele cu catetere venoase centrale, care au suferit interventii chirurgicale recente, aflate sub terapie cu imunosupresoare, precum si cele care prezinta sangerari in materiile fecale sa consulte medicul inainte de administrarea Levurin®.
Continutul plicului de Levurin® se poate dizolva in apa, ceai, sucuri de fructe, iaurt, pireuri de fructe sau legume, nu foarte reci sau fierbinti
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Levurin®
19,75 lei
Composition
One sachet of Levurin® oral powder contains 250 mg of lyophilized powder of Saccharomyces boulardii and 1000 mg of inulin.
Saccharomyces boulardii is a yeast resistant to the action of gastric and intestinal juices, antibiotics and sulfamides, but sensitive to the action of systemic and oral antifungals and quinoline derivatives (strain Saccharomyces boulardii Lessafre CNCM I – 3799 from the product Levurin® is genetically identical to Hansen strain CBS 5926).
Inulin is a polysaccharide of fructose and belongs to the class of carbohydrates known as fructans (inulin from Levurin® is a standardized extract with controlled therapeutic potential).
Mechanism of action
Saccharomyces boulardii can interfere with pathogenesis in the intestinal lumen through several mechanisms: the effect of pathogenic anti-toxins, the effect of inhibiting the development of pathogens, the effect of improving the integrity of the intercellular junction and the trophic effect on the intestinal mucosa.
Saccharomyces boulardii, when administered orally, reaches steady state within 3 days (in the small intestine and colon) and is eliminated within 3-5 days after discontinuation.
Levurin inulin is a substrate for yeast metabolismSaccharomyces boulardii and thus has the potential to support the mechanism of actionSaccharomyces boulardii.
Recommendation
Through the synergistic action of the two components, Levurin® has potential in:
– Prevention and treatment of antibiotic-associated diarrhea
– Prevention of recurrent infections with Clostridium difficile
– Treatment of acute infectious diarrhea
Administration method
On the recommendation of your doctor, Levurin® can be given at the same time as the antibiotic dose.
Levurin® is recommended for adults and children older than 6 months, by oral administration of 1-2 sachets / day, the doses can be increased with the doctor’s advice, if there are no contraindications.
People with central venous catheters who have had recent surgery, undergoing immunosuppressive therapy, as well as those with faecal bleeding should consult their physician before taking Levurin®.
The contents of the Levurin® sachet can be dissolved in water, tea, fruit juices, yoghurt, fruit or vegetable purees, which are not very cold or hot.
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